When do cross-bridges detach from actin?

Study for the Anatomy and Physiology Muscular System Test. Prepare with flashcards and multiple choice questions; each question provides hints and explanations. Get ready to excel in your exam!

Multiple Choice

When do cross-bridges detach from actin?

Explanation:
Detachment of the cross-bridge occurs when ATP binds to the myosin head. This binding reduces myosin’s affinity for actin, causing the myosin head to release from the actin filament. After detachment, ATP is hydrolyzed to ADP and Pi to re-energize and re-cock the head for another cycle. Ca2+ rising is what allows cross-bridge formation by exposing the binding sites on actin through troponin-tropomyosin, while ADP release happens during the power stroke, not detachment.

Detachment of the cross-bridge occurs when ATP binds to the myosin head. This binding reduces myosin’s affinity for actin, causing the myosin head to release from the actin filament. After detachment, ATP is hydrolyzed to ADP and Pi to re-energize and re-cock the head for another cycle. Ca2+ rising is what allows cross-bridge formation by exposing the binding sites on actin through troponin-tropomyosin, while ADP release happens during the power stroke, not detachment.

Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy